Lactobacillus acidophilus is one of the most widely used probiotic species, with clinical trial evidence spanning multiple conditions. It is a component of many multi-strain probiotic formulations and has been tested in RCTs for schizophrenia, breast cancer chemotherapy support, CKD, and hypothyroidism.
Clinical Evidence
- Schizophrenia: Part of multi-strain probiotic (with L. reuteri) + vitamin D that improved metabolic parameters in schizophrenia RCT ghaderi 2019 vitamin d probiotic schizophrenia metabolic rct.
- Hypothyroidism: Synbiotic containing L. acidophilus improved thyroid parameters in hypothyroidism RCT ramezani 2023 synbiotic hypothyroidism rct.
- Breast cancer: Probiotic support during chemotherapy; reviewed for breast cancer treatment khazaei 2023 synbiotics chemotherapy breast cancer rct mendoza 2019 probiotics breast cancer treatment review.
- CKD: Part of probiotic combination pilot for CKD wang 2021 probiotic combination ckd pilot study.
- Reproductive health: Component of FMT protocols for reproductive tract diseases quaranta 2019 fmt female reproductive tract diseases.
Cross-References
- lactobacillus — genus page
- probiotics general — broader probiotic intervention context
- probiotics lactobacillus bifidobacterium — common combination formulations