Ingest Resume — 2026 04 20

Last completed commit

`08e3a047` — ingest: PMDD batch 4 — 3 new source pages

Session summary

Ingested 20 source pages from `raw/Premenstrual Dysphoric Disorder (PMDD)/` folder (15 new, 5 expanded):

New source pages created (15):

  1. `bengi-2025-pmdd-pms-mood-disorder-comorbidity-meta-analysis.md` — PMDD/PMS–mood disorder comorbidity, 42-49% bidirectional (BJPsych, SR/MA)
  2. `gao-2023-allopregnanolone-gaba-receptor-pmdd.md` — ALLO-GABA_A receptor sensitivity, sepranolone (Frontiers Psychiatry, review)
  3. `lin-2023-gut-microbiota-perimenopausal-panic-disorder.md` — Gut microbiota in perimenopausal panic, n=80 (Frontiers Psychiatry, case-control)
  4. `liu-2014-gaba-glutamate-pmdd-mrs.md` — GABA/Glx MRS in PMDD, n=44 (Psychiatry Research: Neuroimaging)
  5. `shi-2024-dietary-patterns-premenstrual-disorders-china.md` — TSCD inversely associated with PMDs, n=1382 (Food & Function)
  6. `yang-2025-pmdd-alzheimers-predisposing-review.md` — PMDD as AD precursor, 5 shared mechanisms (Frontiers Endocrinology)
  7. `yu-2025-microbiota-gut-brain-perimenopausal-depression.md` — MGB axis in PMD, F/B ratio, SCFAs (Expert Reviews Molecular Medicine)
  8. `slyepchenko-2021-comorbid-pmdd-bipolar-review.md` — BD-PMDD comorbidity, 10-21% prevalence (Frontiers Psychiatry)
  9. `takeda-2023-premenstrual-disorders-pms-pmdd-review.md` — Comprehensive PMD overview (J Obstet Gynaecol Res)
  10. `syan-2018-brain-structure-function-bipolar-pmdd.md` — Brain MRI BD+PMDD, n=85 (Frontiers Psychiatry)
  11. `draper-2018-menstrual-cycle-metabolomics.md` — Menstrual cycle metabolomics, 208 metabolites rhythmic, n=34 (Scientific Reports)
  12. `guo-2025-radish-seed-diet-gut-brain-perimenopausal.md` — RSL diet pilot, gut-brain, n=10 (Scientific Reports)
  13. `nguyen-2017-steroid-metabolome-pmdd-gnrh-suppression.md` — PMDD steroid metabolome, sulfotransferase hypothesis, n=30 (Translational Psychiatry)
  14. `sundstrom-poromaa-2023-pmdd-pharmacology-sprm.md` — PMDD pharmacology, ulipristal acetate SPRM (CNS Drugs)
  15. `liang-2023-gut-microbiome-reproductive-endocrine-mr.md` — Gut microbiome → PCOS/endometriosis/infertility MR (Frontiers Endocrinology)

Expanded source pages (5):

  • `takeda-2022-gut-microbiota-premenstrual-symptoms.md`
  • `yao-2024-gut-microbiota-menstrual-disorders-mr.md`
  • `etyemez-2025-biomarkers-reproductive-psychiatric-disorders.md`
  • `li-2020-dietary-fiber-depression-premenopausal-swan.md`
  • `pan-2025-microbiome-targeted-treatment-depression-meta-analysis.md`

Misfiled papers identified (not ingested as PMDD):

  • Preterm birth (s12866-023-02892-z)
  • MS progression (s41598-024-64369-x)
  • Metoprolol/HTN metabolomics (s40246-020-00260-w)
  • Heavy metals/ADHD children (s41598-025-00680-5) — relevant for metals entity, not PMDD
  • Adolescent menstrual health/RTIs (s12982-025-00485-x)
  • Synbiotic/metabolic syndrome rats (s41598-021-00601-2)
  • Honeybee foulbrood (s41598-023-28085-2)
  • Fine motor skills/menstrual cycle (s41598-024-65823-6)
  • Schizophrenia MetS (s12888-024-05969-9)
  • CRC metagenomics (s41591-025-03693-9, Nature Medicine)
  • T3SS immune modulation (s41564-025-02241-y, Nature Microbiology)
  • UC atorvastatin, UC FMT, PCOS metformin/liraglutide, PCOS exercise, PCOS virome, PCOS drospirenone/metformin
  • PsychologyOfAnger, HormoneFix bonus PDF
  • Wei 2022 editorial, Rauniyar 2023 PPD thesis (negative), Kelvin 2021 (weak n=85), Ni 2025 (qualitative psychedelic thesis)

Skipped but potentially ingestable under other conditions:

  • s41598-025-00680-5 (heavy metals/ADHD children) — for metals entity pages
  • s41564-025-02241-y (T3SS immune modulation) — for virulence enzymes concept

Next intended batch (priority order)

  1. Remaining PMDD PDFs (~20 files): numbered unknowns (140161462, 1742-4755-8-2, 19146011_PHR, 20, 211109020633106, 32051, p918, p1239, EmanPublisher, FSHW, s10068, s12905, s12986, s13300, s43088, s44220), plus named ones (Premenstrual_Syndrome.PDF, premenstrual-syndrome.pdf, FMT for female repro tract, air pollution, fungus CNS, acupoint dysmenorrhea, Rosso PhD thesis, female repro health microbiome, personalized microbiota-driven therapies)
  2. PMDD disease entity page creation/update
  3. PMDD signature page build (sufficient sources now: ~21 PMDD-relevant pages)
  4. Fibromyalgia folder (58 PDFs, 7 source pages — next condition per resume-2026-04-19)

Anomalies to watch for

  • High misfiling rate in PMDD folder (~40% of PDFs were not PMDD-relevant)
  • Several PCOS papers misfiled here — check if already ingested under PCOS condition
  • Two papers with same first author (Takeda 2022, Takeda 2023) — different studies, both valuable